Integral mini-channels fabricated in the metal substrate by friction stir channeling process are different from conventional mini-channels due to irregular shape, and large surface roughness. The effect of axial wall conduction on heat transfer in such mini-channels is significant, which could limit their utilisation as cooling channels in heat transfer based applications. Hence, in this study, we present an experimental analysis of the thermo-hydraulic performance of a friction stir channel to identify the axial wall conduction effect using de-ionized water as working fluid. The thermo-hydraulic performance parameters are analysed in the range of Reynolds number of 500 to 2100. The local wall temperature distribution along the length of the mini-channel is found to be non-uniform due to the significant axial wall conduction effect. The distinct pattern of numerical heat flux distribution is used as evidence to confirm the presence of axial wall conduction effect which is implied by the local wall temperature distribution. The higher average heat transfer and flow characteristics compared to the theoretical predictions for conventional mini-channels are observed as a result of simultaneously developing flow and the presence of surface roughness.